Compare MiraLAX's PEG 3350 vs. Relief: Tested, Softened Stool Naturally We’ve tried our fair share of constipation relief, but MiraLAX has consistently impressed us with its gentle yet effective formula. As an osmotic laxative, MiraLAX’s PEG 3350 works naturally by drawing water into the intestines, softening stool without harsh side effects. Unlike some options that leave us feeling crampy or washed out, MiraLAX’s PEG 3350 delivers smooth, predictable results—perfect for long-term relief. The 45-dose packets are convenient, too, ensuring we’re never caught off guard. We appreciate that it dissolves completely in water, avoiding gritty textures. For anyone seeking a comfortable, natural way to soften stool, MiraLAX’s PEG 3350 stands out as a reliable choice.